Posted by: Prof. K. Mohanapriya

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Goldenseal is used to cure skin and eye irritations as well as diarrhoea. It has antibacterial properties as well. Additionally, it is an unproven remedy for colds. The plant alkaloid berberine, which is found in goldenseal, has a lengthy history of therapeutic application in Chinese and Ayurvedic medicine.

Native to North America, goldenseal (Hydrastis canadensis) is an herb. For years, it has been utilised in conventional medicine to address a range of conditions, including infections, inflammation, and digestive issues. Goldenseal is currently one of the most widely used herbal supplements in the US.


Several substances found in goldenseal are believed to have therapeutic benefits, including:

Berberine: This substance has anti-inflammatory, antifungal, and antibacterial qualities. Additionally, it might aid in lowering cholesterol and blood sugar levels. The chemical hydroxyzine possesses anti-inflammatory and anti-tumor characteristics.

Canadine: This substance has anti-inflammatory and antibacterial qualities.


The following conditions are frequently treated with goldenseal:

Goldenseal is frequently used to reduce the length of cold and flu symptoms. Nonetheless, additional investigation is required to validate its efficacy.

Upper respiratory infections: The symptoms of upper respiratory infections, such as sore throats and sinus infections, may be lessened by using goldenseal.

digestive issues: The symptoms of digestive issues, such as constipation, diarrhoea, and stomachaches, may be relieved by using goldenseal.

Skin issues: Rashes, wounds, and other skin conditions can all be treated with goldenseal applied topically.


Goldenseal is available in a variety of forms, including:

Capsules are a handy way to take goldenseal. They are often standardised to contain a particular amount of berberine.

Tinctures: Tinctures are liquid extracts made from goldenseal. They can be ingested or applied topically.

Powders: You can include powders in other recipes, drinks, and smoothies.

Goldenseal is generally safe for most people as long as it is administered according to recommended dosages. Having said that, consult your doctor before using it as it may conflict with certain drugs.


Possible side effects of goldenseal include:

Stomachache: Goldenseal may result in unsettled stomach symptoms such as diarrhoea, vomiting, and nausea.

Low blood pressure: There may be a lowering effect of goldenseal. Before using it, people with low blood pressure should consult their doctor.

Slow heartbeat: The heartbeat may be slowed with goldenseal. Before using it, people with a sluggish heartbeat should consult their doctor.

Goldenseal should not be taken by women who are nursing or pregnant. Goldenseal cannot take the place of medical attention. Please visit a doctor if you have any worries regarding your health.

Reproductive Tract Infections

According to certain research, goldenseal may be a useful treatment for urinary tract infections (UTIs). Berberine and the alkaloids found in the plant’s roots and rhizomes may help stop bacteria from sticking to the bladder’s walls.


Canker Sores

Goldenseal is sometimes used to treat canker sores or oral ulcers. The National Library of Medicine (NLM) states that goldenseal’s berberine may help with the symptoms of canker sores. Topical berberine may help reduce the symptoms of canker sores, according to a 2018 review of research; nonetheless, the authors pointed out that more extensive, carefully planned studies are required. By ingestion, goldenseal only absorbs a limited amount of berberine into the bloodstream. This implies that for goldenseal to be successful, you could not be getting enough berberine from the herb. Therefore, even though berberine has been studied, goldenseal may not benefit from these findings. To assess the effects of goldenseal on canker sores more thoroughly, well-designed human studies are required.



One occasionally uses goldenseal for diabetes. In patients with this illness, the berberine in goldenseal may somewhat lower blood glucose (sugar). Actually, a study that included randomised controlled trials (RCTs) revealed that berberine may lower blood sugar levels in a number of methods, such as by preventing the absorption of glucose from the intestines. Your pancreas may secrete more insulin, a hormone that occurs naturally if you take berberine. Additionally, berberine may lower blood sugar by increasing the sensitivity of your fat and muscle cells to the actions of insulin. However, only a small amount of goldenseal taken orally enters the bloodstream. The National Centre for Integrative and Complementary Health. Goldseal because of this, findings related to berberine may not hold true for goldenseal. Better human studies are required to evaluate goldenseals.


Support for the Immune System

Goldenseal supplements are occasionally used to increase immunity. To prevent the common cold and other viral infections, it is sometimes taken with echinacea. Nevertheless, there hasn’t been any solid scientific proof to back up this application.



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